KEY WORDS | neurons, microtubule, neuroscience |
CITY | Paris |
COUNTRY | France |
DETAILS OF THE OFFER | Working place: The NeuroCyto lab is looking to hire a postdoctoral fellow for an exciting project on novel mechanisms of microtubule turnover in neurons, in collaboration with collaboration with the lab of Manuel Théry and Laurent Blanchoin (CytoMorpho lab, ESPCI, Paris). Missions: The Théry lab has discovered a new mechanism of microtubule turnover via in-lattice repair (Schaedel et al., 2015; Aumeier et al., 2016; Théry & Blanchoin, 2021) that we could recently visualize using super-resolution microscopy (Gazzola et al., 2022). We are now developing methods to visualize in-lattice repair within the dense arrays of neuronal microtubules, and are mapping microtubule turnover in neurons with unprecedented spatial and temporal resolution. The project will explore how in-lattice turnover impacts the establishment, maintenance and transformation of the unique cytoskeletal architecture in neurons, using a combination of single-cell manipulation and advanced microscopy approaches in neuronal cultures. You will drive this project with supervision and mentoring from established researchers in the NeuroCyto lab: devise experiments, acquire and analyze data, work with team members, and prepare publications. Qualifications: We are looking for candidates with a recent PhD in neurobiology or cell biology and a track record of publications and lab experience in one or more areas that include: cytoskeleton, neuronal polarity, advanced microscopy (live-cell imaging, expansion microscopy). Highly motivated candidates with an interest in areas of research at the intersection of neuronal cell biology, advanced microscopy and quantitative biology are strongly encouraged to apply. Taste for interdisciplinary work, team spirit, ability to interact and collaborate with team members and collaborators, a general sense of camaraderie and motivation to learn are a must. |
TYPE OF JOB | Postdoc |
TYPE OF CONTRACT | CDD (temporary / 3 years) |
APPLICATION DEADLINE | 30 NOV 2024 |
EMPLOYMENT START DATE | JAN 2025 |