République Française Inserm
Institut thématique Neurosciences, sciences cognitives, neurologie, psychiatrie

Postdoctoral in Molecular and Cellular Neuroscience

Type of contract CDD

Location Paris, France

Statut Available


Key Words neurogenetic, Huntington disease, neuroscience

Details of the offer

Place of work: Brain institute / Institut du Cerveau

Missions:

Alexandra Durr and Sandrine Humbert’s team focus on neurogenetic diseases, spinocerebellar degenerations (spastic paraplegias and cerebellar ataxias) and Huntington disease. These rare conditions share a late onset even though the mutant genes are expressed since conception and are critical for brain development. Our team showed that brain development is altered in Huntington disease, one of this rare inherited disease, and that these alterations contribute to the late onset. 

Aim: identifying the underlying mechanism of the cellular and circuits defects in the cerebellar ataxia and Huntington disease developing brain and how these disturbances will impact the aging brain decades later.

Qualifications:

We are seeking a highly motivated scientist. Experience in cellular and mouse biology is required.


Additional knowledge in gene expression profiling (analysis of single nuclei RNA sequencing), cortical development and neurological disorders would be a plus.

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Type of job

Type of contract CDD

Application deadline

Employment start date

Contact

Sending a detailed CV including a list of publications, a brief outline of current research, scientific interests and career goals, as well as the name and contact details of references to Alexandra Durr and Sandrine Humbert.

Apply on our career site with your resume and cover letter in English in a single document.